New Step by Step Map For naga 26
New Step by Step Map For naga 26
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The Nagas are divided into different Naga ethnic groups whose quantities and populations are unclear. They Each and every talk unique Naga languages frequently unintelligible into the Other individuals, but all are loosely connected to one another.
Naga figures, for instance Vasuki and Takshaka, also Engage in pivotal roles in different legends, including the churning of the ocean of milk and the epic battles from the Mahabharata. Symbolism and Worship
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Early depictions of circa-9th-century Central Java carefully resembled Indic nāga which was depending on imagery of cobras. In the course of this period, nāga-serpents had been depicted as large cobras supporting the waterspout of yoni-lingam.
There is a proton transfer from your bound drinking water molecule to Asp-273 which is followed by nucleophilic assault to the carbonyl carbon and development from the tetrahedral intermediate. The collapse on the tetrahedral intermediate is facilitated by proton transfer from Asp-273 towards the leaving team amine of the merchandise, d-glucosamine-6-phosphate. The products and solutions depart the active internet site and An additional spherical of catalysis commences Together with the charging of the metallic Centre with a molecule of water from the solvent.
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There is no evidence to counsel that Glu-131 plays any purpose in catalysis other than that can help coordinate the single divalent cation. The enzyme is charge restricted because of the cleavage from the amide bond.
cat vs. pH-profile shown in Figure 2A for Zn-NagA was fit to equation three and these final results show which the deprotonation of only one acid that has a kinetic p
This observation indicates that there has been a divergence from the evolution of NagA and implies there are elementary variations while in the mechanistic facts for substrate activation and hydrolysis. NagA from E. coli
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